The findings, described within the March 30 problem of Nature Biotechnology, provide the first proof that this gene-enhancing method, often known as CRISPR, can reverse disease symptoms in living animals. CRISPR, which offers an easy method to snip out mutated DNA and replace it with the correct sequence, holds potential for treating many genetic issues, based on the research staff. Using a brand new gene-enhancing system based mostly on bacterial proteins, MIT researchers have cured mice of a rare liver dysfunction caused by a single genetic mutation. The mutation — named “the D614G mutation” — occurred on the spike protein, the a part of the virus that helps it bind and fuse to our cells.
Spike mutations are necessary to maintain track of as a result of most vaccines and treatments target these spikes to try and neutralize the virus. This might sound like a fast mutation rate, but in … Read MoreRead More »