Mutation Characterization And Protocols


This disease is brought on by a mutation that causes red blood cells to develop a crescent, or sickle form; this irregular form can result in a variety of well being issues. Some mutations may cause detrimental circumstances similar to Down syndrome or Klinefelter syndrome. However, many mutations are benign, and some even irrelevant, as a result of they exist in areas of DNA that are not actively used.

Vaccinia virus, a DNA virus of the poxvirus group, was used as a live vaccine in the eradication of smallpox. Recombinant vaccinia viruses are being developed that carry vaccinia virus DNA recombined with DNA from other sources (exogenous DNA) (Fig. 43-5). For instance, vaccinia virus strains carrying DNA coding for bacterial and viral antigens have been produced.

Recombination involves the exchange of genetic material between two associated viruses during coinfection of a bunch cell. Mutations can produce viruses with new antigenic … Read More

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