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Although many laboratories publish the decrease limit of a reference interval as “0,” no analytical assay is able to measuring a focus exactly equal to 0 with high reproducibility. All quantitative assays have a finite lower restrict of detection (LLD), distinct from zero, that more precisely constitutes the decrease limit of the reference interval when this lower restrict encompasses 0. Therefore, any PSA worth lower than 0.05 ng/mL could be reported appropriately as “lower than 0.05 ng/mL” and never as zero.0 ng/mL. In addition, it is very important do not forget that reference … Read MoreRead More »