Acute tracheobronchitis is the earliest medical syndrome that outcomes from the poisonous effects of oxygen on the respiratory system. It doesn’t develop in people respiratory oxygen at partial pressures of beneath 0.05 MPa (0.5 ATA or 50% oxygen at normal atmospheric pressure). In healthy humans respiration greater than ninety five% oxygen at regular atmospheric stress (zero.1 MPa), tracheobronchitis develops after a latent interval of 4 to 22 hours and should happen as early as 3 hours while respiration oxygen at 0.3 MPa (three ATA) . It can begin as a light tickling sensation, later adopted by substernal misery and inspiratory pain, which can be accompanied by cough and, when more severe, by a continuing retrosternal burning sensation.
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